Fact checked byKristen Dowd
Source:

Craig A, et al. Abstract 29. Presented at: Infectious Diseases Society for Obstetrics and Gynecology Annual Meeting; Aug. 4-6, 2022; Boston.

Disclosures:Craig reports no relevant financial disclosures.
August 08, 2022
2 min read
Save

Delivery during hospitalization for COVID-19 more likely with non-omicron variants

Fact checked byKristen Dowd
Source:

Craig A, et al. Abstract 29. Presented at: Infectious Diseases Society for Obstetrics and Gynecology Annual Meeting; Aug. 4-6, 2022; Boston.

Disclosures:Craig reports no relevant financial disclosures.
You've successfully added你的提醒。当新的内容发布时,您将收到一封电子邮件。

Click Here to Manage Email Alerts

We were unable to process your request. Please try again later. If you continue to have this issue please contactcustomerservice@slackinc.com.

Pregnant patients with COVID-19 who were hospitalized for symptomatic disease were more likely to deliver during their stay if they were admitted to the hospital during non-omicron pandemic waves, data showed.

Specifically, the rate of delivery during hospitalization for symptomatic disease — which the researchers termed “delivery for COVID-19” — was highest in patients who delivered during the delta wave.

Pregnant patients with COVID-19 who delivered during the delta wave of the pandemic were more likely to deliver during hospitalization for COVID-19 compared with those delivering in other waves. Source: Adobe Stock
Pregnant patients with COVID-19 who delivered during the delta wave of the pandemic were more likely to deliver during hospitalization for COVID-19 compared with those delivering in other waves. Source: Adobe Stock

Additionally, the findings — which were presented at the Infectious Diseases Society for Obstetrics and Gynecology Annual Meeting — supported existing research on the rate ofadverse pregnancy outcomesand the effect ofvaccination in pregnant people.

“Patients with COVID-19 diagnosed in pregnancy, specifically during the delta wave, had higher rates of adverse pregnancy complications when compared to other strains,”Amanda Craig, MD,a maternal-fetal medicine fellow at Duke University School of Medicine, told Healio. “More importantly, COVID-19 vaccination was protective against delivery for COVID-19.”

克雷格和同事回顾了2020年3月至2022年2月25日在杜克大学卫生系统分娩的451名COVID-19患者的电子病历。他们评估了每一波疫情中COVID-19的分娩率、早产率、妊娠高血压疾病和剖宫产率。

In total, 133 (25.3%) patients delivered during the wild-type wave between March and September 2020, 99 (18.8%) delivered during the alpha wave between November 2020 and March 2021, 62 (11.8%) delivered during the delta wave between August and October 2021 and 157 (29.8%) delivered during the omicron wave from December 2021 to February 2022.

Eleven patients had a delivery for COVID-19, all of whom were symptomatic and unvaccinated. There were significant differences between waves, with the greatest number of patients who delivered for COVID-19 doing so during the delta wave (n = 5). Notably, the odds of delivery for COVID-19 were 13 times higher in the delta vs. omicron wave.

There were also significant differences between waves for hypertensive disorders of pregnancy, with patients who delivered in the delta wave being twice as likely to have these disorders as those who delivered in the omicron wave.

早产在队列中很常见(18.8%),没有随波变化。剖宫产分娩在不同的波浪中也没有变化。

“Our findings support initiatives focused on the importance of counseling patients considering pregnancy or currently pregnant about COVID-19 vaccination, particularly as we expect future COVID-19 variants with unknown virulence,” Craig told Healio. “Next steps include looking into duration of protection of COVID-19 vaccines and vaccine boosters during pregnancy, and potential timing for additional boosters in pregnancy.”